| A Case of Systemic Lupus Erythematosus Presenting as Aseptic Meningitis |
| Mi-hwa Kim, MD, Dong-Gun Kim, MD, Young-Ho Koo, MD, Seung-Hun Oh, MD, Hyun Sook Kim, MD, Won-Chan Kim, MD and Ok Joon Kim, MD, PhD |
| Department of Neurology, College of Medicine, Pochon CHA University, Seongnam, Korea |
| A Case of Systemic Lupus Erythematosus Presenting as Aseptic Meningitis |
| Mi-hwa Kim, MD Dong-Gun Kim, MD, Young-Ho Koo, MD, Seung-Hun Oh, MD, Hyun Sook Kim, MD, Won-Chan Kim, MD and Ok Joon Kim, MD, PhD |
| Department of Neurology, College of Medicine, Pochon CHA University, Seongnam, Korea |
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| ABSTRACT |
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organ systems. Although various neuropsychiatric manifestations occur in SLE, development of aseptic meningitis as an initial manifestation is rare.
Case Report: A 26- year-old woman with fever, headache and vomiting was diagnosed with aseptic meningitis in cerebrospinal fluid study. Neuroimaging studies were not remarkable, and hematologic study showed mild leucopenia and thromocytopenia. After 12 days of conservative management, high fever, leucopenia, thrombocytopenia, malar rash and cervical lymph nodes enlargement developed. She had subsequent pleural and pericardial effusions. The rheumatoid factor and anti-nuclear antibody (ANA) were positive and SLE was diagnosed based on clinical manifestations and laboratory studies. After treatments with intravenous immunoglobulin, corticosteroid, antibiotics and hydrochloroquine sulfate, her symptoms gradually improved.
Conclusions: We report a rare case with aseptic meningitis as an initial manifestation of SLE. |
| Key Words:
Systemic lupus erythematosus·Aseptic meningitis |
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