A Case of Multicentric Gliomatosis Cerebri Diagnosed with Brain Biopsy
Dong-Gun Kim, MD and Hyun Sook Kim, MD
Department of Neurology, Bundang CHA Medical Center, CHA University College of Medicine, Seongnam, Korea
ABSTRACT
Background: Gliomatosis cerebri (GC) is a rare subtype of the CNS glioma and about 300 cases of GC are reported hitherto. Among those cases, multicentric GC was exceedingly uncommon. Case Report: A 63-year-old man was admitted with dizziness, nausea, and vomiting. Brain magnetic resonance image showed multiple, non-contiguous brain lesions in corpus callosum, right thalamus, midbrain and frontal and temporal cortices. The 14-3-3 protein was identified temporarily in this patient. Brain biopsy was performed to confirm the diagnosis and anaplastic astrocytoma was found at the right frontal cortex. Conclusions: This is the case report of pathologically confirmed GC with multicentric brain lesions.
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