머리 염색약 사용과 연관이 있을 것으로 추정되는 뇌경색 1예 |
박민근1·권석범1·김예림1·김지애1·이미정1·장윤정1·홍성숙2·강석윤1·정 산1·황성희1 |
한림대학교 의과대학 신경과학교실,1 순천향대학교 의과대학 영상의학과학교실2 |
A Case of Cerebral Infarction Possibly Associated with Para-Phenylenediamine |
Min-Keun Park, MD1, Seok-Beom Kwon, MD1, Ye-Rim Kim, MD1, Ji-Ae Kim, MD1, Mi-Jung Lee, MD1, Yun-Jung Jang, MD1, Seong-Sook Hong, MD, PhD2, Suk Yun Kang, MD1, San Jung |
1Department of Neurology, Hallym University College of Medicine, Seoul, Korea, 2Department of Radiology, Soonchunhyang University College of Medicine, Seoul, Korea |
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ABSTRACT |
Background: Permanent hair dyes are most commonly based on para-phenylenediamine (PPD). Adverse effects of cutaneous PPD intoxication are various from contact dermatitis to severe anaphylaxis. On the contrary, there was no report of PPD induced cerebrovascular disease. Case Report: A 55-year-old diabetic man was adimitted to an intensive care unit because of left visual field defect and left side weakness 2 days after hair dye exposure. He had mild periorbital and facial edema. Neurological examination revealed left homonymous hemianopsia and left hemiparesis (MRC grade IV). Laboratory studies showed a high serum glucose, elevated serum osmolarity and serum creatinine. Diffusion weighted imaging revealed multiple high signal intensities in the right MCA and PCA territories. He was patch-tested for PPD, which was positive. Conclusions: To our knowledge, this case is the first report of cerebral infarction developed after the exposure of PPD in a compromised diabetic patient. |
Key Words:
Cerebral infarction · Para-phenylenediamine · Hair dyes |
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