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J Neurocrit Care 2012;5(2): 61-64.
원발성 가역적뇌혈관수축증후군에 의한 가역적후뇌병증
최윤호·조유나·고 원·류철형·김원주·최영철
연세대학교 의과대학 강남세브란스병원 신경과학교실
Posterior Reversible Encephalopathy Syndrome Due to Primary Reversible Cerebral Vasoconstriction Syndrome
Yun Ho Choi, MD, Yu Na Cho, MD, Won Ko, MD, Chul Hyoung Lyoo, MD, PhD, Won-Joo Kim, MD, PhD and Young-Chul Choi, MD, PhD
Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
ABSTRACT
Background: Reversible cerebral vasoconstriction syndrome (RCVS) is an underdiagnosed disease characterized by severe headaches with or without seizures, focal neurological deficits, and constriction of cerebral arteries which resolves spontaneously in 1-3 months. Posterior reversible encephalopathy syndrome (PRES) is typically characterized by headache, altered mental functioning, seizures, and visual loss associated with imaging findings of bilateral subcortical and cortical edema with a predominantly posterior distribution.
Case Report: We present 49-year-old and 46-year-old females with thunderclap headache and seizure. MRI shows reversible cortical and subcortical lesions in both fronto-parieto-occipital lobes. And magnetic resonance angiography shows reversible multifocal luminal narrowing of distal cerebral vessels.
Conclusions: Primary RCVS may occur as a cause of PRES. We report two cases of non-hypertensive PRES with seizure due to primary RCVS presenting thunderclap headache.
Key Words: Reversible cerebral vasoconstriction syndrome · Posterior reversible encephalopathy syndrome · Thunderclap headache
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