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J Neurocrit Care 2013;6(1): 40-42.
Multiple Intracranial Aneurysms from Syphilitic Infection in a Patient with Acute Ischemic Stroke
Min-Jeong Wang, MD, Sang-Won Yoo, MD, Dong-Woo Ryu, MD, Young-Min Shon, MD, PhD, Beum Saeng Kim, MD, PhD and A-Hyun Cho, MD, PhD
Department of Neurology, The Catholic University of Korea College of Medicine, Yeouido St. Mary’s Hospital, Seoul, Korea
ABSTRACT
Background: Multiple intracranial aneurysms from syphilitic infection have been rarely reported. In this context, we aimed to report a case of multiple intracranial aneurysms incidentally found in a patient with confirmed syphilis and acute ischemic stroke.
Case Report: A 62-year-old woman presented with right sided weakness and dysarthria. The brain MRI and CT angiography revealed acute left middle cerebral arterial territory infarction and incidentally found multiple intracranial aneurysms. On coronary CT angiography, minimal aneurysmal dilatation of right proximal coronary artery was also observed. Blood tests were positive for rapid plasma reasin (RPR) test and fluorescence treponemal antibody absorption test (FTA-ABS) IgM, whereas the cerebrospinal tests for syphilis were negative. The cerebrospinal fluid tests for syphilis were negative for RPR and FTA-ABS. She was diagnosed with latent syphilis.
Conclusions: This case shows a rare case of central nervous system manifestation from syphilitic infection, presented as multiple intracranial aneurysms which were incidentally found in a patient with acute ischemic stroke.
Key Words: Intracranial aneurysm · Syphilis · Stroke
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