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J Neurocrit Care 2013;6(2): 59-66.
급성뇌경색 후 출혈변환: 발생빈도, 예측인자, 그리고 발생기전
이 주 헌
한림대학교 의과대학 강동성심병원 신경과학교실
Hemorrhagic Transformation after Acute Ischemic Stroke: Prevalence, Predictive Factors, and Mechanisms
Ju-Hun Lee, MD
Department of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
Hemorrhagic transformation (HTr) is a complication of acute ischemic stroke which frequently occur as part of the natural evolution of ischemia/reperfusion. Although patients with HTr are often asymptomatic, symptomatic HTr is a cause of early neurologic deterioration and contributes to poor long-term outcome. Therefore, prediction of symptomatic HTr has been an important clinical issue. Here, we reviewed the prevalence of HTr, the predictors for HTr, and its pathophysiological mechanisms related to blood brain barrier.
Key Words: Hemorrhagic transformation · Blood brain barrier
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